January 2019: Congrats to our collaborators, Joris De Wit and Bart De Strooper laboratories, for revealing the physiological role of sAPP/GABA(B1a)R interactions! [PDF]
December 2018: Congrats to Inna, Naomi Habib (HUJI) and Orly Reiner (WIS) for receiving the MOST China-Israel Flagship Project in Brain Sciences!
December 2018: Leore and Ortal – welcome to the Slutsky Lab!
October 2018: Shiri and Nadav – welcome to the Slutsky Lab!
July 31, 2018: Farewell party for Neta who is starting PostDoc in Dr. Stephan Lammel lab at Berkeley!
February 5, 2018: Congrats to Boaz – our perspective on FHP hypothesis is online in Nature Neuroscience!
January 3, 2018: Contgrats to Sam – our review on Alzheimer’s disease is online in Neuron!
July 20, 2017: Graduation of Edden and Neta
July 2, 2017: Congrats to Neta for receiving Sackler faculty best publication award!
December 19, 2016: Slutsky lab received Sackler excellence award!
December 8, 2016: Gabi and Ira received BrainBoost postdoctoral fellowships!
November 30, 2016: Inna received ERC consolidator grant!
July 5, 2016: Nir received TEVA doctoral fellowships!
June 29, 2016: Congrats to Inna for receiving teaching excellence award!
May 23, 2016: Congrats to Neta for receiving Sieratzki Prize for the best publication among PhD students!
December 18, 2015: Congrats to Neta on two occasions: she got a new baby and a paper in Neuron in one week! Here is our video abstract [IGF-1R]
September 16, 2015: Congrats to Slutsky lab for winning Sackler Faculty of Medicine Excellence Award for publishing in the highest impact journals! Ira and Boaz received travel awards for best publications!
June 2, 2015: Congrats to Edden for receiving best publication award among MD/PhD students!
May 14, 2015: Congrats to Ira!
Our paper on the role of GABABRs in firing rate homeostasis has been accepted in PNAS. This work demonstrates that basal activity of GABABRs is essential for homeostatic regulation of synaptic strength by controlling (1) synatxin-1 conformational switch; (2) spike-evoked presynaptic Ca2+ flux; (3) quantal excitatory amplitude. We propose that deficits in GABABR signaling, associated with epilepsy and psychiatric disorders, may lead to aberrant brain activity by erasing homeostatic plasticity.
This work was a fruitful collaboration with the laboratories of Prof. Bernhard Bettler and Prof. Ilana Lotan.
May 14, 2015: Congrats to Boaz for winning 2015 Gertner Fellowship of excellence!
December 31, 2014: Congrats to Edden and Boaz!
Our paper on the interplay between population firing stability and single neuron dynamics has been accepted in eLife. This work demonstrates that invariant ongoing population dynamics emerge from intrinsically unstable activity patterns of individual neurons and synapses. Moreover, it challenges cell-autonomous theory of network homeostasis and suggests existence of network-wide regulation rules.
This work was a fruitful collaboration with Prof. Eli Nelken and Dr. Michael Slutsky.
May 2014: Distinguished Mentor Award to Inna
March 2014: Congrats to Hilla and Samuel! Oshik, Ilana and all the lab members and our collaborators who participated in this project!
Our paper on the mechanism underlying Aβ-induced presynaptic hyperactivity has been accepted in Cell Reports! It demonstrates that APP homodimers constitute a presynaptic receptor for amyloid-beta. This work was a fruitful collaboration with structural biologist Prof. Joel Hirsch (TAU), biophysicists Prof. Ehud Isacoff and Dr. Shashank Bharill (UC Berkeley), biochemists Prof. Dominic Walsh and Tiernan O’Malley (Harvard).
March 2014: Congrats to Tania for receiving Dan David Scholarship!
February 2014: Congrats to Neta for receiving best presentation award of Sagol School for Neuroscience!
November 2013: Congrats to Samuel for receiving Marie Curie CIG grant!
June 19, 2013: Brain pannel at the 2013 Isareli President’s Conference [Tomorrow]
May 10, 2013: Congrats to Iftach and Hilla for receiving Sieratzki prize for the best publication!
April 25, 2013: Congrats to Iftach and Hilla!
Our paper is finally out in Nature Neuroscience! It demonstrates regulation of amyloid-beta 40/42 ratio by spiking patterns, filter properties of synapses and sensory experience.
April 25, 2013: Congrats to Iftach for the approval of his PhD thesis!
May 02, 2013: Congrats to Irena for receiving the National Network of Excellence in Neuroscience Post-Doctoral Fellowship Award!